Paraoxonase/MCS.
نویسنده
چکیده
The Focus article "Double Exposure" [EHP 107:A196-A201 (1999)] mistakenly reported that a meta-analysis of epidemiology studies examining the relationship between exposure to environmental tobacco smoke (ETS) and human cancer was prepared for the review of ETS in consideration for listing in the National Toxicology Program (NTP) Report on Carcinogens. We would like to point out that the results of several published metaanalyses were considered during the ETS review, but that the NTP did not, in fact, perform an additional meta-analysis of these data.
منابع مشابه
Evaluation of structure of paraoxonase (PON) and its relationship with various diseases
The paraoxonase family in humans includes the PON1, PON2, and PON3 genes. These genes are located on the long arm of chromosome 7 and are structurally similar .Between the nucleotide sequences of these three genes is about 70% and between their amino acid sequences is about 60% compatibility. The three have 9 exons, which in the case of PON1 exists an addition code in position 106 (lysine) i...
متن کاملمطالعه فنوتیپ‌ها و فعالیت آنزیم پارااکسوناز در بیماران مبتلا به گرفتگی عروق کرونر
Paraoxonase can hydrolyse organophosphate esters and paraxon is its most important substrate in laboratory studies. This enzyme circulates in blood with HDL. It seems that reduced paraoxonase activity in human may increase risk of coronary artery disease. Genetic variations in two autosomal genes may reduce its activity. These variations produce three phenotypes: A, AB and B. B phenotype ac...
متن کاملParaoxonase Inhibition by Propranolol
There are many evidences that human serum paraoxonase activity modifies plasma lipid profile and paraoxonase has an antiatherogenic property. Non-selective beta-blockers affect plasma lipid profile too, but they have atherogenic property when patients take these drugs in long term. In this study the effect of propranolol, a non-selective beta-blocker, on paraoxonase activity was investigated. L...
متن کاملParaoxonase Inhibition by Propranolol
There are many evidences that human serum paraoxonase activity modifies plasma lipid profile and paraoxonase has an antiatherogenic property. Non-selective beta-blockers affect plasma lipid profile too, but they have atherogenic property when patients take these drugs in long term. In this study the effect of propranolol, a non-selective beta-blocker, on paraoxonase activity was investigated. L...
متن کاملEffect of Pomegranate Juice on Paraoxonase Enzyme Activity in Patients with Type 2 Diabetes
OBJECTIVE: The aim of this study was to investigate the effect of pomegranate juice (PJ) on the paraoxonase and arylesterase activity of human serum paraoxonase( PON1). MATERIAL AND METHOD: Fifty patients with type 2 diabetes mellitus consumed 200 ml of PJ daily for a period of 6 weeks. Blood was collected from the patients before and after PJ consumption after 12 h of fasting. Blood sugar, to...
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ورودعنوان ژورنال:
- Environmental Health Perspectives
دوره 107 شماره
صفحات -
تاریخ انتشار 1999